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Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level
BACKGROUND: Mortality from colorectal cancer is mainly due to metastatic liver disease. Improved understanding of the molecular events underlying metastasis is crucial for the development of new methods for early detection and treatment of colorectal cancer. Loss of chromosome 8p is frequently seen...
Autores principales: | Macartney-Coxson, Donia P, Hood, Kylie A, Shi, Hong-jun, Ward, Teresa, Wiles, Anna, O'Connor, Rosemary, Hall, David A, Lea, Rod A, Royds, Janice A, Stubbs, Richard S, Rooker, Serena |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488356/ https://www.ncbi.nlm.nih.gov/pubmed/18590575 http://dx.doi.org/10.1186/1471-2407-8-187 |
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