Cargando…

Role of Peroxisome Proliferator-Activated Receptor Alpha in the Control of Cyclooxygenase 2 and Vascular Endothelial Growth Factor: Involvement in Tumor Growth

A growing body of evidence indicates that PPAR (peroxisome proliferator-activated receptor) α agonists might have therapeutic usefulness in antitumoral therapy by decreasing abnormal cell growth, and reducing tumoral angiogenesis. Most of the anti-inflammatory and antineoplastic properties of PPAR l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grau, Raquel, Díaz-Muñoz, Manuel D., Cacheiro-Llaguno, Cristina, Fresno, Manuel, Iñiguez, Miguel A.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2008
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490577/ https://www.ncbi.nlm.nih.gov/pubmed/18670614 http://dx.doi.org/10.1155/2008/352437

Ejemplares similares

Regulation of Cyclooxygenase-2 Expression in Human T Cells by Glucocorticoid Receptor-Mediated Transrepression of Nuclear Factor of Activated T Cells
por: Cacheiro-Llaguno, Cristina, et al.
Publicado: (2022)

Selective Inhibition of Vascular Endothelial Growth Factor–Mediated Angiogenesis by Cyclosporin a: Roles of the Nuclear Factor of Activated T Cells and Cyclooxygenase 2
por: Hernández, Gabriela L., et al.
Publicado: (2001)

Peroxisome proliferator-activated receptor alpha agonist suppresses neovascularization by reducing both vascular endothelial growth factor and angiopoietin-2 in corneal alkali burn
por: Arima, Takeshi, et al.
Publicado: (2017)

Cyclooxygenase-2 and vascular endothelial growth factor in chronic hepatitis, cirrhosis and hepatocellular carcinoma
por: Kwon, Soon Ha, et al.
Publicado: (2012)

Cyclooxygenase Isoenzyme-2 and Vascular Endothelial Growth Factor are Associated with Poor Prognosis in Esophageal Adenocarcinoma
por: Prins, M. J. D., et al.
Publicado: (2012)

Cyclooxygenase-2-expressing macrophages in human pterygium co-express vascular endothelial growth factor
por: Park, Choul Yong, et al.
Publicado: (2011)

Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
por: Valcárcel, María, et al.
Publicado: (2011)

Sulindac Derivatives That Activate the Peroxisome Proliferator-activated Receptor γ but Lack Cyclooxygenase Inhibition
por: Felts, Andrew S., et al.
Publicado: (2008)

Vascular endothelial growth factor promotes the expression of cyclooxygenase 2 and matrix metalloproteinases in Lewis lung carcinoma cells
por: HU, JIANWU, et al.
Publicado: (2012)

Mechanisms Involved in the Enhanced Susceptibility of Senescent Rats to the Hepatocarcinogenic Effect of Peroxisome Proliferators: Role of Peroxisome Proliferator-Activated Receptor alpha (PPAR), Cell Proliferation and Oxidative Stress
por: Youssef, Jihan A., et al.
Publicado: (2001)

Baohuoside I Inhibits Tumor Angiogenesis in Multiple Myeloma via the Peroxisome Proliferator–Activated Receptor γ/Vascular Endothelial Growth Factor Signaling Pathway
por: Chen, Ying, et al.
Publicado: (2022)

Peroxisome Proliferator-Activated Receptor Alpha Target Genes
por: Rakhshandehroo, Maryam, et al.
Publicado: (2010)

Palmitoylethanolamide Modulates Inflammation-Associated Vascular Endothelial Growth Factor (VEGF) Signaling via the Akt/mTOR Pathway in a Selective Peroxisome Proliferator-Activated Receptor Alpha (PPAR-α)-Dependent Manner
por: Sarnelli, Giovanni, et al.
Publicado: (2016)

Clinical implication of expression of cyclooxygenase-2 and peroxisome proliferator activated-receptor γ in epithelial ovarian tumours
por: Sakamoto, A, et al.
Publicado: (2004)

Peroxisome proliferator-activated receptor alpha is involved in the temperature-induced sex differentiation of a vertebrate
por: Hara, Seiji, et al.
Publicado: (2020)

Involvement of Angiopoietin 2 and vascular endothelial growth factor in uveitis
por: Suzuki, Kayo, et al.
Publicado: (2023)

Peroxisome proliferator-activated receptor γ mediates porcine placental angiogenesis through hypoxia inducible factor-, vascular endothelial growth factor- and angiopoietin-mediated signaling
por: Zhang, Juzuo, et al.
Publicado: (2017)

Inhibition of hypoxia-induced cyclooxygenase-2 by Korean Red Ginseng is dependent on peroxisome proliferator-activated receptor gamma
por: Song, Heewon, et al.
Publicado: (2017)

Adaptation of peroxisome proliferator-activated receptor alpha to hibernation in bats
por: Han, Yijie, et al.
Publicado: (2015)

Ginsenoside Rf inhibits cyclooxygenase-2 induction via peroxisome proliferator–activated receptor gamma in A549 cells
por: Song, Heewon, et al.
Publicado: (2019)

Cyclooxygenase-2 and Prostaglandin E(2) Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection
por: Guerrero, Néstor A., et al.
Publicado: (2015)

Effects of L-carnitine against oxidative stress in human hepatocytes: involvement of peroxisome proliferator-activated receptor alpha
por: Li, Jin-Lian, et al.
Publicado: (2012)

Vascular endothelial growth factors and vascular permeability
por: Bates, David O.
Publicado: (2010)

Correction: Cyclooxygenase-2 and Prostaglandin E2 Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection
por: Guerrero, Néstor A., et al.
Publicado: (2015)

The Role of Peroxisome Proliferator-Activated Receptors in Pulmonary Vascular Disease
por: Nisbet, Rachel E., et al.
Publicado: (2007)

Role of Peroxisome Proliferator-Activated Receptor-γ in Vascular Inflammation
por: Ohshima, Kousei, et al.
Publicado: (2012)

Role of Circulating Immune Complexes in the Pathogenesis of Canine Leishmaniasis: New Players in Vaccine Development
por: Cacheiro-Llaguno, Cristina, et al.
Publicado: (2021)

Comparison of vascular endothelial growth factor/vascular endothelial growth factor receptor 2 expression and its relationship to tumor cell proliferation in canine epithelial and mesenchymal tumors
por: KIMURA, Mayu, et al.
Publicado: (2021)

Cyclooxygenase 2 (COX2) and Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Are Stage-Dependent Prognostic Markers of Malignant Melanoma
por: Meyer, Stefanie, et al.
Publicado: (2010)

Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer
por: Luo, Honghe, et al.
Publicado: (2011)

Helicobacter pylori promotes angiogenesis depending on Wnt/beta-catenin-mediated vascular endothelial growth factor via the cyclooxygenase-2 pathway in gastric cancer
por: Liu, Ningning, et al.
Publicado: (2016)

Bioactive phytoconstituents of ethanolic extract from Chromolaena odorata leaves interact with vascular endothelial growth factor and cyclooxygenase-2: A molecular docking study
por: Teuku Husni, TR, et al.
Publicado: (2023)

Vitreous levels of vascular endothelial growth factor in eyes with anterior hyaloidal fibrovascular proliferation
por: Kobayashi, Takaki, et al.
Publicado: (2010)

The role of vascular endothelial growth factor in proliferation of odontogenic cysts and tumors: An immunohistochemical study
por: Gupta, Bhavana, et al.
Publicado: (2016)

Peroxisome Proliferator-Activated Receptor γ Regulates the Expression of Lipid Phosphate Phosphohydrolase 1 in Human Vascular Endothelial Cells
por: Huang, Yazi, et al.
Publicado: (2014)

The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Protects Vascular Endothelial Function in Hypercholesterolemic Rats by Inhibiting Myeloperoxidase
por: Zhang, Dapeng, et al.
Publicado: (2020)

Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) in rats.
por: Reddy, J. K., et al.
Publicado: (1979)

Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha
por: Li, Guolin, et al.
Publicado: (2017)

Hepatic Peroxisome Proliferator-Activated Receptor Alpha Dysfunction in Porcine Septic Shock
por: Vandewalle, Jolien, et al.
Publicado: (2022)

Mechanistic insights into the peroxisome proliferator-activated receptor alpha as a transcriptional suppressor
por: Yagai, Tomoki, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m2baq9jsam46h8jkv3sdobcjt9