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Accumulation of GC donor splice signals in mammals
The GT dinucleotide in the first two intron positions is the most conserved element of the U2 donor splice signals. However, in a small fraction of donor sites, GT is replaced by GC. A substantial enrichment of GC in donor sites of alternatively spliced genes has been observed previously in human, n...
Autores principales: | Churbanov, Alexander, Winters-Hilt, Stephen, Koonin, Eugene V, Rogozin, Igor B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490688/ https://www.ncbi.nlm.nih.gov/pubmed/18613975 http://dx.doi.org/10.1186/1745-6150-3-30 |
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