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Suppression of HIV-Specific and Allogeneic T Cell Activation by Human Regulatory T Cells Is Dependent on the Strength of Signals

Regulatory T cells (Tregs) suppress immune responses against both self and non-self antigens. Tregs require activation through the T cell receptor (TCR) and IL-2 to exert their suppressive functions. However, how strength of TCR signals modulate the potency of Treg-mediated suppression of antigen-sp...

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Detalles Bibliográficos
Autores principales: Antons, Amanda K., Wang, Rui, Kalams, Spyros A., Unutmaz, Derya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490715/
https://www.ncbi.nlm.nih.gov/pubmed/18698349
http://dx.doi.org/10.1371/journal.pone.0002952