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Effect of polymorphisms within probe–target sequences on olignonucleotide microarray experiments
Hybridization-based technologies, such as microarrays, rely on precise probe-target interactions to ensure specific and accurate measurement of RNA expression. Polymorphisms present in the probe–target sequences have been shown to alter probe- hybridization affinities, leading to reduced signal inte...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490733/ https://www.ncbi.nlm.nih.gov/pubmed/18596082 http://dx.doi.org/10.1093/nar/gkn409 |