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Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule
During assembly, HLA class II molecules associate with the invariant chain. As the result, the peptide-binding groove is occupied by an invariant chain peptide termed CLIP (class-II-associated invariant chain peptide; sequence MRMATPLLM). By mass spectrometry, we have now characterized peptides that...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491419/ https://www.ncbi.nlm.nih.gov/pubmed/18584168 http://dx.doi.org/10.1007/s00251-008-0310-6 |