Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule

During assembly, HLA class II molecules associate with the invariant chain. As the result, the peptide-binding groove is occupied by an invariant chain peptide termed CLIP (class-II-associated invariant chain peptide; sequence MRMATPLLM). By mass spectrometry, we have now characterized peptides that...

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Detalles Bibliográficos
Autores principales: Wiesner, Martina, Stepniak, Dariusz, de Ru, Arnoud H., Moustakis, Antonis K., Drijfhout, Jan W., Papadopoulos, George K., van Veelen, Peter A., Koning, Frits
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491419/
https://www.ncbi.nlm.nih.gov/pubmed/18584168
http://dx.doi.org/10.1007/s00251-008-0310-6

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