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FDG uptake, a surrogate of tumour hypoxia?
INTRODUCTION: Tumour hyperglycolysis is driven by activation of hypoxia-inducible factor-1 (HIF-1) through tumour hypoxia. Accordingly, the degree of 2-fluro-2-deoxy-d-glucose (FDG) uptake by tumours might indirectly reflect the level of hypoxia, obviating the need for more specific radiopharmaceuti...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Springer-Verlag
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491423/ https://www.ncbi.nlm.nih.gov/pubmed/18509637 http://dx.doi.org/10.1007/s00259-008-0758-5 |