APOBEC3G encapsidation into HIV-1 virions: which RNA is it?

APOBEC3G is a cytidine deaminase with potent antiviral activity. The protein deaminates single-stranded DNA but is known to bind cellular and viral RNAs. There is increasing evidence that RNA binding of APOBEC3G is important for packaging into viral particles. However, there is no consensus yet on t...

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Detalles Bibliográficos
Autores principales: Strebel, Klaus, Khan, Mohammad A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491656/
https://www.ncbi.nlm.nih.gov/pubmed/18597677
http://dx.doi.org/10.1186/1742-4690-5-55
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author Strebel, Klaus
Khan, Mohammad A
author_facet Strebel, Klaus
Khan, Mohammad A
author_sort Strebel, Klaus
collection PubMed
description APOBEC3G is a cytidine deaminase with potent antiviral activity. The protein deaminates single-stranded DNA but is known to bind cellular and viral RNAs. There is increasing evidence that RNA binding of APOBEC3G is important for packaging into viral particles. However, there is no consensus yet on the type of RNA involved.
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spelling pubmed-24916562008-07-31 APOBEC3G encapsidation into HIV-1 virions: which RNA is it? Strebel, Klaus Khan, Mohammad A Retrovirology Commentary APOBEC3G is a cytidine deaminase with potent antiviral activity. The protein deaminates single-stranded DNA but is known to bind cellular and viral RNAs. There is increasing evidence that RNA binding of APOBEC3G is important for packaging into viral particles. However, there is no consensus yet on the type of RNA involved. BioMed Central 2008-07-02 /pmc/articles/PMC2491656/ /pubmed/18597677 http://dx.doi.org/10.1186/1742-4690-5-55 Text en Copyright © 2008 Strebel and Khan; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Strebel, Klaus
Khan, Mohammad A
APOBEC3G encapsidation into HIV-1 virions: which RNA is it?
title APOBEC3G encapsidation into HIV-1 virions: which RNA is it?
title_full APOBEC3G encapsidation into HIV-1 virions: which RNA is it?
title_fullStr APOBEC3G encapsidation into HIV-1 virions: which RNA is it?
title_full_unstemmed APOBEC3G encapsidation into HIV-1 virions: which RNA is it?
title_short APOBEC3G encapsidation into HIV-1 virions: which RNA is it?
title_sort apobec3g encapsidation into hiv-1 virions: which rna is it?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491656/
https://www.ncbi.nlm.nih.gov/pubmed/18597677
http://dx.doi.org/10.1186/1742-4690-5-55
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