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Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor, p27Xic1

AIMS: Cyclin-dependent kinase inhibitors (CDKIs) play a critical role in negatively regulating the proliferation of cardiomyocytes, although their role in cardiac differentiation remains largely undetermined. We have shown that the most prominent CDKI in Xenopus, p27(Xic1)(Xic1), plays a role in neu...

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Detalles Bibliográficos
Autores principales: Movassagh, Mehregan, Philpott, Anna
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2492727/
https://www.ncbi.nlm.nih.gov/pubmed/18442987
http://dx.doi.org/10.1093/cvr/cvn105