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Protein kinase B/Akt activity is involved in renal TGF-β1-driven epithelial-mesenchymal transition in vitro and in vivo

The molecular pathogenesis of diabetic nephropathy (DN), the leading cause of end-stage renal disease worldwide, is complex and not fully understood. Transforming growth factor-β (TGF-β1) plays a critical role in many fibrotic disorders, including DN. In this study, we report protein kinase B (PKB/A...

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Detalles Bibliográficos
Autores principales:	Kattla, Jayesh J., Carew, Rosemarie M., Heljić, Mediha, Godson, Catherine, Brazil, Derek P.
Formato:	Texto
Lenguaje:	English
Publicado:	American Physiological Society 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494512/ https://www.ncbi.nlm.nih.gov/pubmed/18495798 http://dx.doi.org/10.1152/ajprenal.00548.2007

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