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Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder
Slowing of the rate at which a rivalrous percept switches from one configuration to another has been suggested as a potential trait marker for bipolar disorder. We measured perceptual alternations for a bistable, rotating, structure-from-motion cylinder in bipolar and control participants. In a cont...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Royal Society
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494571/ https://www.ncbi.nlm.nih.gov/pubmed/18463054 http://dx.doi.org/10.1098/rspb.2008.0043 |
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author | Krug, Kristine Brunskill, Emma Scarna, Antonina Goodwin, Guy M Parker, Andrew J |
author_facet | Krug, Kristine Brunskill, Emma Scarna, Antonina Goodwin, Guy M Parker, Andrew J |
author_sort | Krug, Kristine |
collection | PubMed |
description | Slowing of the rate at which a rivalrous percept switches from one configuration to another has been suggested as a potential trait marker for bipolar disorder. We measured perceptual alternations for a bistable, rotating, structure-from-motion cylinder in bipolar and control participants. In a control task, binocular depth rendered the direction of cylinder rotation unambiguous to monitor participants' performance and attention during the experimental task. A particular direction of rotation was perceptually stable, on average, for 33.5 s in participants without psychiatric diagnosis. Euthymic, bipolar participants showed a slightly slower rate of switching between the two percepts (percept duration 42.3 s). Under a parametric analysis of the best-fitting model for individual participants, this difference was statistically significant. However, the variability within groups was high, so this difference in average switch rates was not big enough to serve as a trait marker for bipolar disorder. We also found that low-level visual capacities, such as stereo threshold, influence perceptual switch rates. We suggest that there is no single brain location responsible for perceptual switching in all different ambiguous figures and that perceptual switching is generated by the actions of local cortical circuitry. |
format | Text |
id | pubmed-2494571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-24945712008-12-08 Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder Krug, Kristine Brunskill, Emma Scarna, Antonina Goodwin, Guy M Parker, Andrew J Proc Biol Sci Research Article Slowing of the rate at which a rivalrous percept switches from one configuration to another has been suggested as a potential trait marker for bipolar disorder. We measured perceptual alternations for a bistable, rotating, structure-from-motion cylinder in bipolar and control participants. In a control task, binocular depth rendered the direction of cylinder rotation unambiguous to monitor participants' performance and attention during the experimental task. A particular direction of rotation was perceptually stable, on average, for 33.5 s in participants without psychiatric diagnosis. Euthymic, bipolar participants showed a slightly slower rate of switching between the two percepts (percept duration 42.3 s). Under a parametric analysis of the best-fitting model for individual participants, this difference was statistically significant. However, the variability within groups was high, so this difference in average switch rates was not big enough to serve as a trait marker for bipolar disorder. We also found that low-level visual capacities, such as stereo threshold, influence perceptual switch rates. We suggest that there is no single brain location responsible for perceptual switching in all different ambiguous figures and that perceptual switching is generated by the actions of local cortical circuitry. The Royal Society 2008-05-07 2008-08-22 /pmc/articles/PMC2494571/ /pubmed/18463054 http://dx.doi.org/10.1098/rspb.2008.0043 Text en Copyright © 2008 The Royal Society http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Krug, Kristine Brunskill, Emma Scarna, Antonina Goodwin, Guy M Parker, Andrew J Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder |
title | Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder |
title_full | Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder |
title_fullStr | Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder |
title_full_unstemmed | Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder |
title_short | Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder |
title_sort | perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494571/ https://www.ncbi.nlm.nih.gov/pubmed/18463054 http://dx.doi.org/10.1098/rspb.2008.0043 |
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