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Obese Mice Lacking Inducible Nitric Oxide Synthase Are Sensitized to the Metabolic Actions of Peroxisome Proliferator–Activated Receptor-γ Agonism

OBJECTIVE—Synthetic ligands for peroxisome proliferator–activated receptor-γ (PPAR-γ) improve insulin sensitivity in obesity, but it is still unclear whether inflammatory signals modulate their metabolic actions. In this study, we tested whether targeted disruption of inducible nitric oxide (NO) syn...

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Detalles Bibliográficos
Autores principales:	Dallaire, Patrice, Bellmann, Kerstin, Laplante, Mathieu, Gélinas, Stéphanie, Centeno-Baez, Carolina, Penfornis, Patrice, Peyot, Marie-Line, Latour, Martin G., Lamontagne, Julien, Trujillo, Maria E., Scherer, Philipp E., Prentki, Marc, Deshaies, Yves, Marette, André
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494686/ https://www.ncbi.nlm.nih.gov/pubmed/18458147 http://dx.doi.org/10.2337/db08-0540

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