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Angiotensin II Type 1 Receptor Signaling Contributes to Synaptophysin Degradation and Neuronal Dysfunction in the Diabetic Retina

OBJECTIVE—Pathogenic mechanisms underlying diabetes-induced retinal dysfunction are not fully understood. The aim of the present study was to show the relationship of the renin-angiotensin system (RAS) with the synaptic vesicle protein synaptophysin and neuronal activity in the diabetic retina. RESE...

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Detalles Bibliográficos
Autores principales:	Kurihara, Toshihide, Ozawa, Yoko, Nagai, Norihiro, Shinoda, Kei, Noda, Kousuke, Imamura, Yutaka, Tsubota, Kazuo, Okano, Hideyuki, Oike, Yuichi, Ishida, Susumu
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494692/ https://www.ncbi.nlm.nih.gov/pubmed/18487452 http://dx.doi.org/10.2337/db07-1281

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