Consequences of Lipid Droplet Coat Protein Downregulation in Liver Cells: Abnormal Lipid Droplet Metabolism and Induction of Insulin Resistance

OBJECTIVE—Accumulation of intracellular lipid droplets (LDs) in non-adipose tissues is recognized as a strong prognostic factor for the development of insulin resistance in obesity. LDs are coated with perilipin, adipose differentiation–related protein, tail interacting protein of 47 kd (PAT) protei...

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Detalles Bibliográficos
Autores principales: Bell, Ming, Wang, Hong, Chen, Hui, McLenithan, John C., Gong, Da-Wei, Yang, Rong-Zee, Yu, Daozhan, Fried, Susan K., Quon, Michael J., Londos, Constantine, Sztalryd, Carole
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494696/
https://www.ncbi.nlm.nih.gov/pubmed/18487449
http://dx.doi.org/10.2337/db07-1383

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