T Cells' Immunological Synapses Induce Polarization of Brain Astrocytes In Vivo and In Vitro: A Novel Astrocyte Response Mechanism to Cellular Injury

BACKGROUND: Astrocytes usually respond to trauma, stroke, or neurodegeneration by undergoing cellular hypertrophy, yet, their response to a specific immune attack by T cells is poorly understood. Effector T cells establish specific contacts with target cells, known as immunological synapses, during...

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Detalles Bibliográficos
Autores principales: Barcia, Carlos, Sanderson, Nicholas S. R., Barrett, Robert J., Wawrowsky, Kolja, Kroeger, Kurt M., Puntel, Mariana, Liu, Chunyan, Castro, Maria G., Lowenstein, Pedro R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496894/
https://www.ncbi.nlm.nih.gov/pubmed/18714338
http://dx.doi.org/10.1371/journal.pone.0002977

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