Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes

BACKGROUND: The greatest challenges in vaccine development include optimization of DNA vaccines for use in humans, creation of effective single-dose vaccines, development of delivery systems that do not involve live viruses, and the identification of effective new adjuvants. Herein, we describe a no...

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Detalles Bibliográficos
Autores principales: Rosada, Rogério S, Torre, Lucimara Gaziola de la, Frantz, Fabiani G, Trombone, Ana PF, Zárate-Bladés, Carlos R, Fonseca, Denise M, Souza, Patrícia RM, Brandão, Izaíra T, Masson, Ana P, Soares, Édson G, Ramos, Simone G, Faccioli, Lúcia H, Silva, Célio L, Santana, Maria HA, Coelho-Castelo, Arlete AM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500095/
https://www.ncbi.nlm.nih.gov/pubmed/18647414
http://dx.doi.org/10.1186/1471-2172-9-38

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