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Microtubule cross-linking triggers the directional motility of kinesin-5
Although assembly of the mitotic spindle is known to be a precisely controlled process, regulation of the key motor proteins involved remains poorly understood. In eukaryotes, homotetrameric kinesin-5 motors are required for bipolar spindle formation. Eg5, the vertebrate kinesin-5, has two modes of...
Autores principales: | Kapitein, Lukas C., Kwok, Benjamin H., Weinger, Joshua S., Schmidt, Christoph F., Kapoor, Tarun M., Peterman, Erwin J.G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500128/ https://www.ncbi.nlm.nih.gov/pubmed/18678707 http://dx.doi.org/10.1083/jcb.200801145 |
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