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Stochastic and Regulatory Role of Chromatin Silencing in Genomic Response to Environmental Changes
Phenotypic diversity and fidelity can be balanced by controlling stochastic molecular mechanisms. Epigenetic silencing is one that has a critical role in stress response. Here we show that in yeast, incomplete silencing increases stochastic noise in gene expression, probably owing to unstable chroma...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500160/ https://www.ncbi.nlm.nih.gov/pubmed/18714342 http://dx.doi.org/10.1371/journal.pone.0003002 |