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OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation

BACKGROUND: Identification of tumor suppressor genes (TSGs) silenced by CpG methylation uncovers the molecular mechanism of tumorigenesis and potential tumor biomarkers. Loss of heterozygosity at 11q25 is common in multiple tumors including nasopharyngeal carcinoma (NPC). OPCML, located at 11q25, is...

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Detalles Bibliográficos
Autores principales:	Cui, Yan, Ying, Ying, van Hasselt, Andrew, Ng, Ka Man, Yu, Jun, Zhang, Qian, Jin, Jie, Liu, Dingxie, Rhim, Johng S., Rha, Sun Young, Loyo, Myriam, Chan, Anthony T. C., Srivastava, Gopesh, Tsao, George S. W., Sellar, Grant C., Sung, Joseph J. Y., Sidransky, David, Tao, Qian
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500176/ https://www.ncbi.nlm.nih.gov/pubmed/18714356 http://dx.doi.org/10.1371/journal.pone.0002990

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