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Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells

Alk(en)yl trisulfides (R-SSS-R′) are organosulfur compounds produced by crushed garlic and other Allium vegetables. We found that these compounds exhibit potent anticancer effects through the reaction with microtubules, causing cell cycle arrest. Nine alk(en)yl trisulfides including dimethyl trisulf...

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Detalles Bibliográficos
Autores principales: Hosono, Takashi, Hosono-Fukao, Tomomi, Inada, Kahoru, Tanaka, Rie, Yamada, Haruhisa, Iitsuka, Yuji, Seki, Taiichiro, Hasegawa, Isao, Ariga, Toyohiko
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500214/
https://www.ncbi.nlm.nih.gov/pubmed/18515280
http://dx.doi.org/10.1093/carcin/bgn124