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Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells
Alk(en)yl trisulfides (R-SSS-R′) are organosulfur compounds produced by crushed garlic and other Allium vegetables. We found that these compounds exhibit potent anticancer effects through the reaction with microtubules, causing cell cycle arrest. Nine alk(en)yl trisulfides including dimethyl trisulf...
Autores principales: | Hosono, Takashi, Hosono-Fukao, Tomomi, Inada, Kahoru, Tanaka, Rie, Yamada, Haruhisa, Iitsuka, Yuji, Seki, Taiichiro, Hasegawa, Isao, Ariga, Toyohiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500214/ https://www.ncbi.nlm.nih.gov/pubmed/18515280 http://dx.doi.org/10.1093/carcin/bgn124 |
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