Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway

Glypican-3 (gpc3) is the gene responsible for Simpson-Golabi-Behmel overgrowth syndrome. Previously, we have shown that GPC3 is overexpressed in hepatocellular carcinoma (HCC). In this study, we demonstrated the mechanisms for GPC3-mediated oncogenesis. Firstly, GPC3 overexpression in NIH3T3 cells g...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Wei, Tseng, Chia-Jen, Lin, Tom T.C., Cheng, I., Pan, Hung-Wei, Hsu, Hey-Chi, Lee, Yu-May
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500215/
https://www.ncbi.nlm.nih.gov/pubmed/18413366
http://dx.doi.org/10.1093/carcin/bgn091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500215/
https://www.ncbi.nlm.nih.gov/pubmed/18413366
http://dx.doi.org/10.1093/carcin/bgn091

Ejemplares similares