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Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway

Glypican-3 (gpc3) is the gene responsible for Simpson-Golabi-Behmel overgrowth syndrome. Previously, we have shown that GPC3 is overexpressed in hepatocellular carcinoma (HCC). In this study, we demonstrated the mechanisms for GPC3-mediated oncogenesis. Firstly, GPC3 overexpression in NIH3T3 cells g...

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Detalles Bibliográficos
Autores principales:	Cheng, Wei, Tseng, Chia-Jen, Lin, Tom T.C., Cheng, I., Pan, Hung-Wei, Hsu, Hey-Chi, Lee, Yu-May
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500215/ https://www.ncbi.nlm.nih.gov/pubmed/18413366 http://dx.doi.org/10.1093/carcin/bgn091

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