The therapeutic effects of Rho-ROCK inhibitors on CNS disorders

Rho-kinase (ROCK) is a serine/threonine kinase and one of the major downstream effectors of the small GTPase Rho. The Rho-ROCK pathway is involved in many aspects of neuronal functions including neurite outgrowth and retraction. The Rho-ROCK pathway becomes an attractive target for the development o...

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Detalles Bibliográficos
Autores principales: Kubo, Takekazu, Yamaguchi, Atsushi, Iwata, Nobuyoshi, Yamashita, Toshihide
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500253/
https://www.ncbi.nlm.nih.gov/pubmed/18827856

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