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Training the next generation of pluripotent stem cell researchers

Human pluripotent stem cells (PSCs) have the unique properties of being able to proliferate indefinitely in their undifferentiated state and of being able to differentiate into any somatic cell type. These cells are thus posited to be extremely useful for furthering our understanding of both normal...

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Detalles Bibliográficos
Autor principal: Schwartz, Philip Hitchins
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503969/
https://www.ncbi.nlm.nih.gov/pubmed/18651970
http://dx.doi.org/10.1186/1479-5876-6-40
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author Schwartz, Philip Hitchins
author_facet Schwartz, Philip Hitchins
author_sort Schwartz, Philip Hitchins
collection PubMed
description Human pluripotent stem cells (PSCs) have the unique properties of being able to proliferate indefinitely in their undifferentiated state and of being able to differentiate into any somatic cell type. These cells are thus posited to be extremely useful for furthering our understanding of both normal and abnormal human development, providing a human cell preparation that can be used to screen for new reagents or therapeutic agents, and generating large numbers of differentiated cells that can be used for transplantation purposes. PSCs in culture have a specific morphology and they express characteristic surface antigens and nuclear transcription factors; thus, PSC culture is very specific and requires a core skill set for successful propagation of these unique cells. Specialized PSC training courses have been extremely valuable in seeding the scientific community with researchers that possess this skill set.
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spelling pubmed-25039692008-08-08 Training the next generation of pluripotent stem cell researchers Schwartz, Philip Hitchins J Transl Med Editorial Human pluripotent stem cells (PSCs) have the unique properties of being able to proliferate indefinitely in their undifferentiated state and of being able to differentiate into any somatic cell type. These cells are thus posited to be extremely useful for furthering our understanding of both normal and abnormal human development, providing a human cell preparation that can be used to screen for new reagents or therapeutic agents, and generating large numbers of differentiated cells that can be used for transplantation purposes. PSCs in culture have a specific morphology and they express characteristic surface antigens and nuclear transcription factors; thus, PSC culture is very specific and requires a core skill set for successful propagation of these unique cells. Specialized PSC training courses have been extremely valuable in seeding the scientific community with researchers that possess this skill set. BioMed Central 2008-07-23 /pmc/articles/PMC2503969/ /pubmed/18651970 http://dx.doi.org/10.1186/1479-5876-6-40 Text en Copyright © 2008 Schwartz; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Editorial
Schwartz, Philip Hitchins
Training the next generation of pluripotent stem cell researchers
title Training the next generation of pluripotent stem cell researchers
title_full Training the next generation of pluripotent stem cell researchers
title_fullStr Training the next generation of pluripotent stem cell researchers
title_full_unstemmed Training the next generation of pluripotent stem cell researchers
title_short Training the next generation of pluripotent stem cell researchers
title_sort training the next generation of pluripotent stem cell researchers
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503969/
https://www.ncbi.nlm.nih.gov/pubmed/18651970
http://dx.doi.org/10.1186/1479-5876-6-40
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