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Development of an isoform-specific gene suppression system: the study of the human Pax-5B transcriptional element
The transcription factor Pax-5, is vital during B lymphocyte differentiation and is known to contribute to the oncogenesis of certain cancers. The Pax-5 locus generates multiple yet structurally related mRNA transcripts through the specific activation of alternative promoter regions and/or alternati...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504290/ https://www.ncbi.nlm.nih.gov/pubmed/18617575 http://dx.doi.org/10.1093/nar/gkn432 |