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Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream

BACKGROUND: Raised C-reactive protein (CRP) is a risk factor for type 2 diabetes. According to the Mendelian randomization method, the association is likely to be causal if genetic variants that affect CRP level are associated with markers of diabetes development and diabetes. Our objective was to e...

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Detalles Bibliográficos
Autores principales:	Brunner, Eric J, Kivimäki, Mika, Witte, Daniel R, Lawlor, Debbie A, Smith, George Davey, Cooper, Jackie A, Miller, Michelle, Lowe, Gordon D. O, Rumley, Ann, Casas, Juan P, Shah, Tina, Humphries, Steve E, Hingorani, Aroon D, Marmot, Michael G, Timpson, Nicholas J, Kumari, Meena
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504484/ https://www.ncbi.nlm.nih.gov/pubmed/18700811 http://dx.doi.org/10.1371/journal.pmed.0050155

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