MafA and MafB Regulate Pdx1 Transcription through the Area II Control Region in Pancreatic β Cells

Pancreatic-duodenal homeobox factor-1 (Pdx1) is highly enriched in islet β cells and integral to proper cell development and adult function. Of the four conserved 5′-flanking sequence blocks that contribute to transcription in vivo, Area II (mouse base pairs -2153/-1923) represents the only mammalia...

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Detalles Bibliográficos
Autores principales: Vanhoose, Amanda M., Samaras, Susan, Artner, Isabella, Henderson, Eva, Hang, Yan, Stein, Roland
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Transcription, Chromatin, and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504898/
https://www.ncbi.nlm.nih.gov/pubmed/18522939
http://dx.doi.org/10.1074/jbc.M802902200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504898/
https://www.ncbi.nlm.nih.gov/pubmed/18522939
http://dx.doi.org/10.1074/jbc.M802902200

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