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MafA and MafB Regulate Pdx1 Transcription through the Area II Control Region in Pancreatic β Cells
Pancreatic-duodenal homeobox factor-1 (Pdx1) is highly enriched in islet β cells and integral to proper cell development and adult function. Of the four conserved 5′-flanking sequence blocks that contribute to transcription in vivo, Area II (mouse base pairs -2153/-1923) represents the only mammalia...
Autores principales: | Vanhoose, Amanda M., Samaras, Susan, Artner, Isabella, Henderson, Eva, Hang, Yan, Stein, Roland |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504898/ https://www.ncbi.nlm.nih.gov/pubmed/18522939 http://dx.doi.org/10.1074/jbc.M802902200 |
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