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The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case
BACKGROUND: With the 2005 WHO classification of salivary gland tumours and its increasingly recognized diagnostic entities, the frequency of adenocarcinoma (NOS) has decreased significantly. CASE PRESENTATION: This paper describes a fast growing adenocarcinoma (NOS), originating from the minor saliv...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515301/ https://www.ncbi.nlm.nih.gov/pubmed/18667060 http://dx.doi.org/10.1186/1746-160X-4-16 |
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author | Ettl, Tobias Kleinheinz, Johannes Mehrotra, Ravi Schwarz, Stephan Reichert, Torsten Eugen Driemel, Oliver |
author_facet | Ettl, Tobias Kleinheinz, Johannes Mehrotra, Ravi Schwarz, Stephan Reichert, Torsten Eugen Driemel, Oliver |
author_sort | Ettl, Tobias |
collection | PubMed |
description | BACKGROUND: With the 2005 WHO classification of salivary gland tumours and its increasingly recognized diagnostic entities, the frequency of adenocarcinoma (NOS) has decreased significantly. CASE PRESENTATION: This paper describes a fast growing adenocarcinoma (NOS), originating from the minor salivary glands of the left buccal mucosa with a rapid onset of multiple local and distant metastases, especially in the lung. A lung primary was unlikely as the tumour was characterized by positivity for cytokeratin 20 and negativity for the thyroid transcription factor-1 protein (TTF-1) in immunohistochemistry. CONCLUSION: A rare case of an adenocarcinoma (NOS) of the minor salivary glands with a rapid development and an unfavourable clinical course is reported. It shows that additional immunohistochemical analysis can decisively contribute to determine the site of the primary tumour in cases with unknown primary. |
format | Text |
id | pubmed-2515301 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25153012008-08-13 The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case Ettl, Tobias Kleinheinz, Johannes Mehrotra, Ravi Schwarz, Stephan Reichert, Torsten Eugen Driemel, Oliver Head Face Med Case Report BACKGROUND: With the 2005 WHO classification of salivary gland tumours and its increasingly recognized diagnostic entities, the frequency of adenocarcinoma (NOS) has decreased significantly. CASE PRESENTATION: This paper describes a fast growing adenocarcinoma (NOS), originating from the minor salivary glands of the left buccal mucosa with a rapid onset of multiple local and distant metastases, especially in the lung. A lung primary was unlikely as the tumour was characterized by positivity for cytokeratin 20 and negativity for the thyroid transcription factor-1 protein (TTF-1) in immunohistochemistry. CONCLUSION: A rare case of an adenocarcinoma (NOS) of the minor salivary glands with a rapid development and an unfavourable clinical course is reported. It shows that additional immunohistochemical analysis can decisively contribute to determine the site of the primary tumour in cases with unknown primary. BioMed Central 2008-07-30 /pmc/articles/PMC2515301/ /pubmed/18667060 http://dx.doi.org/10.1186/1746-160X-4-16 Text en Copyright © 2008 Ettl et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Ettl, Tobias Kleinheinz, Johannes Mehrotra, Ravi Schwarz, Stephan Reichert, Torsten Eugen Driemel, Oliver The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case |
title | The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case |
title_full | The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case |
title_fullStr | The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case |
title_full_unstemmed | The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case |
title_short | The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case |
title_sort | buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515301/ https://www.ncbi.nlm.nih.gov/pubmed/18667060 http://dx.doi.org/10.1186/1746-160X-4-16 |
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