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RNA interference for CFTR attenuates lung fluid absorption at birth in rats

BACKGROUND: Small interfering RNA (siRNA) against αENaC (α-subunit of the epithelial Na channel) and CFTR (cystic fibrosis transmembrane conductance regulator) was used to explore ENaC and CTFR function in newborn rat lungs. METHODS: Twenty-four hours after trans-thoracic intrapulmonary (ttip) injec...

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Detalles Bibliográficos
Autores principales:	Li, Tianbo, Koshy, Shyny, Folkesson, Hans G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515309/ https://www.ncbi.nlm.nih.gov/pubmed/18652671 http://dx.doi.org/10.1186/1465-9921-9-55

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