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Functional and biochemical characterization of the 20S proteasome in a yeast temperature-sensitive mutant, rpt6-1

BACKGROUND: Rpt6-1 is a thermosensitive yeast mutant with a deletion of a gene encoding a regulatory subunit of the 26S proteasome, RPT6, which is able to grow at 25°C but not at 37°C. In this study, peptidase activities, activation profiles, and the subunit composition of the 20S proteasome purifie...

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Detalles Bibliográficos
Autores principales: Chouduri, Aktar Uzzaman, Tokumoto, Toshinobu, Dohra, Hideo, Ushimaru, Takashi, Yamada, Shinpei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515314/
https://www.ncbi.nlm.nih.gov/pubmed/18644121
http://dx.doi.org/10.1186/1471-2091-9-20