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HIV Traffics through a Specialized, Surface-Accessible Intracellular Compartment during trans-Infection of T Cells by Mature Dendritic Cells

In vitro, dendritic cells (DCs) bind and transfer intact, infectious HIV to CD4 T cells without first becoming infected, a process known as trans-infection. trans-infection is accomplished by recruitment of HIV and its receptors to the site of DC–T cell contact and transfer of virions at a structure...

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Detalles Bibliográficos
Autores principales: Yu, Hyun Jae, Reuter, Morgan A., McDonald, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515344/
https://www.ncbi.nlm.nih.gov/pubmed/18725936
http://dx.doi.org/10.1371/journal.ppat.1000134