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Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit
Understanding how avian influenza viruses adapt to human hosts is critical for the monitoring and prevention of future pandemics. Host specificity is determined by multiple sites in different viral proteins, and mutation of only a limited number of these sites can lead to inter-species transmission....
Autores principales: | Tarendeau, Franck, Crepin, Thibaut, Guilligay, Delphine, Ruigrok, Rob W. H., Cusack, Stephen, Hart, Darren J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515345/ https://www.ncbi.nlm.nih.gov/pubmed/18769709 http://dx.doi.org/10.1371/journal.ppat.1000136 |
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