Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer

The imprinted insulin-like growth factor 2 (IGF2) gene is expressed predominantly from the paternal allele. Loss of imprinting (LOI) associated with hypomethylation at the promoter proximal sequence (DMR0) of the IGF2 gene was proposed as a predisposing constitutive risk biomarker for colorectal can...

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Detalles Bibliográficos
Autores principales: Ito, Yoko, Koessler, Thibaud, Ibrahim, Ashraf E.K., Rai, Sushma, Vowler, Sarah L., Abu-Amero, Sayeda, Silva, Ana-Luisa, Maia, Ana-Teresa, Huddleston, Joanna E., Uribe-Lewis, Santiago, Woodfine, Kathryn, Jagodic, Maja, Nativio, Raffaella, Dunning, Alison, Moore, Gudrun, Klenova, Elena, Bingham, Sheila, Pharoah, Paul D.P., Brenton, James D., Beck, Stephan, Sandhu, Manjinder S., Murrell, Adele
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515372/
https://www.ncbi.nlm.nih.gov/pubmed/18541649
http://dx.doi.org/10.1093/hmg/ddn163

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