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Cancer is a Preventable Disease that Requires Major Lifestyle Changes

This year, more than 1 million Americans and more than 10 million people worldwide are expected to be diagnosed with cancer, a disease commonly believed to be preventable. Only 5–10% of all cancer cases can be attributed to genetic defects, whereas the remaining 90–95% have their roots in the enviro...

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Autores principales: Anand, Preetha, Kunnumakara, Ajaikumar B., Sundaram, Chitra, Harikumar, Kuzhuvelil B., Tharakan, Sheeja T., Lai, Oiki S., Sung, Bokyung, Aggarwal, Bharat B.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515569/
https://www.ncbi.nlm.nih.gov/pubmed/18626751
http://dx.doi.org/10.1007/s11095-008-9661-9
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author Anand, Preetha
Kunnumakara, Ajaikumar B.
Sundaram, Chitra
Harikumar, Kuzhuvelil B.
Tharakan, Sheeja T.
Lai, Oiki S.
Sung, Bokyung
Aggarwal, Bharat B.
author_facet Anand, Preetha
Kunnumakara, Ajaikumar B.
Sundaram, Chitra
Harikumar, Kuzhuvelil B.
Tharakan, Sheeja T.
Lai, Oiki S.
Sung, Bokyung
Aggarwal, Bharat B.
author_sort Anand, Preetha
collection PubMed
description This year, more than 1 million Americans and more than 10 million people worldwide are expected to be diagnosed with cancer, a disease commonly believed to be preventable. Only 5–10% of all cancer cases can be attributed to genetic defects, whereas the remaining 90–95% have their roots in the environment and lifestyle. The lifestyle factors include cigarette smoking, diet (fried foods, red meat), alcohol, sun exposure, environmental pollutants, infections, stress, obesity, and physical inactivity. The evidence indicates that of all cancer-related deaths, almost 25–30% are due to tobacco, as many as 30–35% are linked to diet, about 15–20% are due to infections, and the remaining percentage are due to other factors like radiation, stress, physical activity, environmental pollutants etc. Therefore, cancer prevention requires smoking cessation, increased ingestion of fruits and vegetables, moderate use of alcohol, caloric restriction, exercise, avoidance of direct exposure to sunlight, minimal meat consumption, use of whole grains, use of vaccinations, and regular check-ups. In this review, we present evidence that inflammation is the link between the agents/factors that cause cancer and the agents that prevent it. In addition, we provide evidence that cancer is a preventable disease that requires major lifestyle changes.
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spelling pubmed-25155692008-08-14 Cancer is a Preventable Disease that Requires Major Lifestyle Changes Anand, Preetha Kunnumakara, Ajaikumar B. Sundaram, Chitra Harikumar, Kuzhuvelil B. Tharakan, Sheeja T. Lai, Oiki S. Sung, Bokyung Aggarwal, Bharat B. Pharm Res Expert Review This year, more than 1 million Americans and more than 10 million people worldwide are expected to be diagnosed with cancer, a disease commonly believed to be preventable. Only 5–10% of all cancer cases can be attributed to genetic defects, whereas the remaining 90–95% have their roots in the environment and lifestyle. The lifestyle factors include cigarette smoking, diet (fried foods, red meat), alcohol, sun exposure, environmental pollutants, infections, stress, obesity, and physical inactivity. The evidence indicates that of all cancer-related deaths, almost 25–30% are due to tobacco, as many as 30–35% are linked to diet, about 15–20% are due to infections, and the remaining percentage are due to other factors like radiation, stress, physical activity, environmental pollutants etc. Therefore, cancer prevention requires smoking cessation, increased ingestion of fruits and vegetables, moderate use of alcohol, caloric restriction, exercise, avoidance of direct exposure to sunlight, minimal meat consumption, use of whole grains, use of vaccinations, and regular check-ups. In this review, we present evidence that inflammation is the link between the agents/factors that cause cancer and the agents that prevent it. In addition, we provide evidence that cancer is a preventable disease that requires major lifestyle changes. Springer US 2008-07-15 2008-09 /pmc/articles/PMC2515569/ /pubmed/18626751 http://dx.doi.org/10.1007/s11095-008-9661-9 Text en © Springer Science+Business Media, LLC 2008
spellingShingle Expert Review
Anand, Preetha
Kunnumakara, Ajaikumar B.
Sundaram, Chitra
Harikumar, Kuzhuvelil B.
Tharakan, Sheeja T.
Lai, Oiki S.
Sung, Bokyung
Aggarwal, Bharat B.
Cancer is a Preventable Disease that Requires Major Lifestyle Changes
title Cancer is a Preventable Disease that Requires Major Lifestyle Changes
title_full Cancer is a Preventable Disease that Requires Major Lifestyle Changes
title_fullStr Cancer is a Preventable Disease that Requires Major Lifestyle Changes
title_full_unstemmed Cancer is a Preventable Disease that Requires Major Lifestyle Changes
title_short Cancer is a Preventable Disease that Requires Major Lifestyle Changes
title_sort cancer is a preventable disease that requires major lifestyle changes
topic Expert Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515569/
https://www.ncbi.nlm.nih.gov/pubmed/18626751
http://dx.doi.org/10.1007/s11095-008-9661-9
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