Cargando…

Photocytotoxicity of mTHPC (Temoporfin) Loaded Polymeric Micelles Mediated by Lipase Catalyzed Degradation

PURPOSE: To study the in vitro photocytotoxicity and cellular uptake of biodegradable polymeric micelles loaded with the photosensitizer mTHPC, including the effect of lipase-catalyzed micelle degradation. METHODS: Micelles of mPEG750-b-oligo(ɛ-caprolactone)(5) (mPEG750-b-OCL(5)) with a hydroxyl (OH...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hofman, Jan-Willem, Carstens, Myrra G., van Zeeland, Femke, Helwig, Conny, Flesch, Frits M., Hennink, Wim E., van Nostrum, Cornelus F.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer US 2008
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515570/ https://www.ncbi.nlm.nih.gov/pubmed/18597164 http://dx.doi.org/10.1007/s11095-008-9590-7

Ejemplares similares

EGFR-Targeted Nanobody Functionalized Polymeric Micelles Loaded with mTHPC for Selective Photodynamic Therapy
por: Liu, Yanna, et al.
Publicado: (2020)

Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin): comparison of treatment efficacy and distribution characteristics in vivo
por: Reshetov, Vadzim, et al.
Publicado: (2013)

Lipid‐DNAs as Solubilizers of mTHPC
por: Liu, Yun, et al.
Publicado: (2017)

mTHPC-Loaded Extracellular Vesicles Significantly Improve mTHPC Diffusion and Photodynamic Activity in Preclinical Models
por: Millard, Marie, et al.
Publicado: (2020)

Photodynamic therapy with mTHPC and polyethylene glycol-derived mTHPC: a comparative study on human tumour xenografts
por: Ris, H-B, et al.
Publicado: (1999)

Styrene Maleic Acid Copolymer-Based Micellar Formation of Temoporfin (SMA@ mTHPC) Behaves as A Nanoprobe for Tumor-Targeted Photodynamic Therapy with A Superior Safety
por: Fang, Jun, et al.
Publicado: (2021)

mTHPC-loaded extracellular vesicles outperform liposomal and free mTHPC formulations by an increased stability, drug delivery efficiency and cytotoxic effect in tridimensional model of tumors
por: Millard, Marie, et al.
Publicado: (2018)

Evaluation for Synergistic Effects by Combinations of Photodynamic Therapy (PDT) with Temoporfin (mTHPC) and Pt(II) Complexes Carboplatin, Cisplatin or Oxaliplatin in a Set of Five Human Cancer Cell Lines
por: Lange, Carsten, et al.
Publicado: (2018)

Photodynamic therapy of a transplanted pancreatic cancer model using meta-tetrahydroxyphenylchlorin (mTHPC).
por: Mikvy, P., et al.
Publicado: (1997)

Distribution and photodynamic effects of meso-tetrahydroxyphenylchlorin (mTHPC) in the pancreas and adjacent tissues in the Syrian golden hamster.
por: Mlkvy, P., et al.
Publicado: (1996)

Peripheral neural cell sensitivity to mTHPC-mediated photodynamic therapy in a 3D in vitro model
por: Wright, K E, et al.
Publicado: (2009)

A Mixed Micelle Formulation for Oral Delivery of Vitamin K
por: Sun, Feilong, et al.
Publicado: (2016)

Comparison of Cellular Death Pathways after mTHPC-mediated Photodynamic Therapy (PDT) in Five Human Cancer Cell Lines
por: Lange, Carsten, et al.
Publicado: (2019)

Foscan® (mTHPC) photosensitized macrophage activation: enhancement of phagocytosis, nitric oxide release and tumour necrosis factor-α-mediated cytolytic activity
por: Coutier, S, et al.
Publicado: (1999)

Dithiolane-Crosslinked Poly(ε-caprolactone)-Based Micelles: Impact of Monomer Sequence, Nature of Monomer, and Reducing Agent on the Dynamic Crosslinking Properties
por: Liu, Yanna, et al.
Publicado: (2020)

Uptake and localisation of mTHPC (Foscan®) and its(14)C-labelled form in normal and tumour tissues of the hamster squamous cell carcinoma model: a comparative study
por: Blant, S Andrejevic, et al.
Publicado: (2002)

Effective treatment of liver metastases with photodynamic therapy, using the second-generation photosensitizer meta-tetra(hydroxyphenyl)chlorin (mTHPC), in a rat model
por: Rovers, J P, et al.
Publicado: (1999)

Short- and long-term normal tissue damage with photodynamic therapy in pig trachea: a fluence-response pilot study comparing Photofrin and mTHPC
por: Murrer, L H P, et al.
Publicado: (1999)

A matched cohort comparison of mTHPC-mediated photodynamic therapy and trans-oral surgery of early stage oral cavity squamous cell cancer
por: Karakullukcu, Baris, et al.
Publicado: (2012)

Effect of Formulation and Processing Parameters on the Size of mPEG-b-p(HPMA-Bz) Polymeric Micelles
por: Bagheri, Mahsa, et al.
Publicado: (2018)

Identification and Assessment of Octreotide Acylation in Polyester Microspheres by LC–MS/MS
por: Shirangi, Mehrnoosh, et al.
Publicado: (2015)

Influence of PEGylation of Vitamin-K-Loaded Mixed Micelles on the Uptake by and Transport through Caco-2 Cells
por: Sun, Feilong, et al.
Publicado: (2018)

π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy
por: Liu, Yanna, et al.
Publicado: (2020)

Internalization and Transport of PEGylated Lipid-Based Mixed Micelles across Caco-2 Cells Mediated by Scavenger Receptor B1
por: Su, Xiangjie, et al.
Publicado: (2021)

In Vitro and In Vivo Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin
por: Bagheri, Mahsa, et al.
Publicado: (2021)

Selective Cytotoxicity to HER2 Positive Breast Cancer Cells by Saporin-Loaded Nanobody-Targeted Polymeric Nanoparticles in Combination with Photochemical Internalization
por: Martínez-Jothar, Lucía, et al.
Publicado: (2019)

Modulation of Temoporfin Distribution in Blood by β-Cyclodextrin Nanoshuttles
por: Yakavets, Ilya, et al.
Publicado: (2021)

Receptor-Targeting Phthalocyanine Photosensitizer for Improving Antitumor Photocytotoxicity
por: Xu, Peng, et al.
Publicado: (2012)

Enhanced photocytotoxicity of curcumin delivered by solid lipid nanoparticles
por: Jiang, Shan, et al.
Publicado: (2016)

Utility of Intravenous Curcumin Nanodelivery Systems for Improving In Vivo Pharmacokinetics and Anticancer Pharmacodynamics
por: Bagheri, Mahsa, et al.
Publicado: (2022)

Inhibition of cow’s milk allergy development in mice by oral delivery of β‐lactoglobulin‐derived peptides loaded PLGA nanoparticles is associated with systemic whey‐specific immune silencing
por: Liu, Mengshan, et al.
Publicado: (2021)

Oral pretreatment with β-lactoglobulin derived peptide and CpG co-encapsulated in PLGA nanoparticles prior to sensitizations attenuates cow’s milk allergy development in mice
por: Liu, Mengshan, et al.
Publicado: (2023)

Photocytotoxic Activity of Ruthenium(II) Complexes with Phenanthroline-Hydrazone Ligands
por: Silva-Caldeira, Priscila Pereira, et al.
Publicado: (2021)

Copper(ii) curcumin complexes for endoplasmic reticulum targeted photocytotoxicity
por: Banaspati, Atrayee, et al.
Publicado: (2022)

Hydrophilic Polyester Microspheres: Effect of Molecular Weight and Copolymer Composition on Release of BSA
por: Ghassemi, Amir H., et al.
Publicado: (2010)

Matryoshka-Type Liposomes Offer the Improved Delivery of Temoporfin to Tumor Spheroids
por: Yakavets, Ilya, et al.
Publicado: (2019)

Photoinduced DNA Cleavage and Photocytotoxic of Phenanthroline-Based Ligand Ruthenium Compounds
por: Hu, Xia, et al.
Publicado: (2021)

Photodynamic therapy effect of m-THPC (Foscan®) in vivo: correlation with pharmacokinetics
por: Jones, H J, et al.
Publicado: (2003)

Glycol porphyrin derivatives and temoporfin elicit resistance to photodynamic therapy by different mechanisms
por: Kralova, Jarmila, et al.
Publicado: (2017)

Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells
por: Xiong, Li, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_coulnve6k5h32nnds8gm2pm43a