Neutralization of Botulinum Neurotoxin by a Human Monoclonal Antibody Specific for the Catalytic Light Chain

BACKGROUND: Botulinum neurotoxins (BoNT) are a family of category A select bioterror agents and the most potent biological toxins known. Cloned antibody therapeutics hold considerable promise as BoNT therapeutics, but the therapeutic utility of antibodies that bind the BoNT light chain domain (LC),...

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Detalles Bibliográficos
Autores principales: Adekar, Sharad P., Takahashi, Tsuyoshi, Jones, R. Mark, Al-Saleem, Fetweh H., Ancharski, Denise M., Root, Michael J., Kapadnis, B. P., Simpson, Lance L., Dessain, Scott K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515629/
https://www.ncbi.nlm.nih.gov/pubmed/18714390
http://dx.doi.org/10.1371/journal.pone.0003023

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