The Early ANTP Gene Repertoire: Insights from the Placozoan Genome

The evolution of ANTP genes in the Metazoa has been the subject of conflicting hypotheses derived from full or partial gene sequences and genomic organization in higher animals. Whole genome sequences have recently filled in some crucial gaps for the basal metazoan phyla Cnidaria and Porifera. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Schierwater, Bernd, Kamm, Kai, Srivastava, Mansi, Rokhsar, Daniel, Rosengarten, Rafael D., Dellaporta, Stephen L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515636/
https://www.ncbi.nlm.nih.gov/pubmed/18716659
http://dx.doi.org/10.1371/journal.pone.0002457
_version_ 1782158435861659648
author Schierwater, Bernd
Kamm, Kai
Srivastava, Mansi
Rokhsar, Daniel
Rosengarten, Rafael D.
Dellaporta, Stephen L.
author_facet Schierwater, Bernd
Kamm, Kai
Srivastava, Mansi
Rokhsar, Daniel
Rosengarten, Rafael D.
Dellaporta, Stephen L.
author_sort Schierwater, Bernd
collection PubMed
description The evolution of ANTP genes in the Metazoa has been the subject of conflicting hypotheses derived from full or partial gene sequences and genomic organization in higher animals. Whole genome sequences have recently filled in some crucial gaps for the basal metazoan phyla Cnidaria and Porifera. Here we analyze the complete genome of Trichoplax adhaerens, representing the basal metazoan phylum Placozoa, for its set of ANTP class genes. The Trichoplax genome encodes representatives of Hox/ParaHox-like, NKL, and extended Hox genes. This repertoire possibly mirrors the condition of a hypothetical cnidarian-bilaterian ancestor. The evolution of the cnidarian and bilaterian ANTP gene repertoires can be deduced by a limited number of cis-duplications of NKL and “extended Hox” genes and the presence of a single ancestral “ProtoHox” gene.
format Text
id pubmed-2515636
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-25156362008-08-21 The Early ANTP Gene Repertoire: Insights from the Placozoan Genome Schierwater, Bernd Kamm, Kai Srivastava, Mansi Rokhsar, Daniel Rosengarten, Rafael D. Dellaporta, Stephen L. PLoS One Research Article The evolution of ANTP genes in the Metazoa has been the subject of conflicting hypotheses derived from full or partial gene sequences and genomic organization in higher animals. Whole genome sequences have recently filled in some crucial gaps for the basal metazoan phyla Cnidaria and Porifera. Here we analyze the complete genome of Trichoplax adhaerens, representing the basal metazoan phylum Placozoa, for its set of ANTP class genes. The Trichoplax genome encodes representatives of Hox/ParaHox-like, NKL, and extended Hox genes. This repertoire possibly mirrors the condition of a hypothetical cnidarian-bilaterian ancestor. The evolution of the cnidarian and bilaterian ANTP gene repertoires can be deduced by a limited number of cis-duplications of NKL and “extended Hox” genes and the presence of a single ancestral “ProtoHox” gene. Public Library of Science 2008-08-21 /pmc/articles/PMC2515636/ /pubmed/18716659 http://dx.doi.org/10.1371/journal.pone.0002457 Text en This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. https://creativecommons.org/publicdomain/zero/1.0/ This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
spellingShingle Research Article
Schierwater, Bernd
Kamm, Kai
Srivastava, Mansi
Rokhsar, Daniel
Rosengarten, Rafael D.
Dellaporta, Stephen L.
The Early ANTP Gene Repertoire: Insights from the Placozoan Genome
title The Early ANTP Gene Repertoire: Insights from the Placozoan Genome
title_full The Early ANTP Gene Repertoire: Insights from the Placozoan Genome
title_fullStr The Early ANTP Gene Repertoire: Insights from the Placozoan Genome
title_full_unstemmed The Early ANTP Gene Repertoire: Insights from the Placozoan Genome
title_short The Early ANTP Gene Repertoire: Insights from the Placozoan Genome
title_sort early antp gene repertoire: insights from the placozoan genome
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515636/
https://www.ncbi.nlm.nih.gov/pubmed/18716659
http://dx.doi.org/10.1371/journal.pone.0002457
work_keys_str_mv AT schierwaterbernd theearlyantpgenerepertoireinsightsfromtheplacozoangenome
AT kammkai theearlyantpgenerepertoireinsightsfromtheplacozoangenome
AT srivastavamansi theearlyantpgenerepertoireinsightsfromtheplacozoangenome
AT rokhsardaniel theearlyantpgenerepertoireinsightsfromtheplacozoangenome
AT rosengartenrafaeld theearlyantpgenerepertoireinsightsfromtheplacozoangenome
AT dellaportastephenl theearlyantpgenerepertoireinsightsfromtheplacozoangenome
AT schierwaterbernd earlyantpgenerepertoireinsightsfromtheplacozoangenome
AT kammkai earlyantpgenerepertoireinsightsfromtheplacozoangenome
AT srivastavamansi earlyantpgenerepertoireinsightsfromtheplacozoangenome
AT rokhsardaniel earlyantpgenerepertoireinsightsfromtheplacozoangenome
AT rosengartenrafaeld earlyantpgenerepertoireinsightsfromtheplacozoangenome
AT dellaportastephenl earlyantpgenerepertoireinsightsfromtheplacozoangenome

Ejemplares similares