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Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1

BACKGROUND: A number of prostaglandins (PGs) sensitize dorsal root ganglion (DRG) neurons and contribute to inflammatory hyperalgesia by signaling through specific G protein-coupled receptors (GPCRs). One mechanism whereby PGs sensitize these neurons is through modulation of "thermoTRPs,"...

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Detalles Bibliográficos
Autores principales:	Cruz-Orengo, Lillian, Dhaka, Ajay, Heuermann, Robert J, Young, Timothy J, Montana, Michael C, Cavanaugh, Eric J, Kim, Donghee, Story, Gina M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515828/ https://www.ncbi.nlm.nih.gov/pubmed/18671867 http://dx.doi.org/10.1186/1744-8069-4-30

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