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Heterogeneity in multistage carcinogenesis and mixture modeling
Carcinogenesis is commonly described as a multistage process, in which stem cells are transformed into cancer cells via a series of mutations. In this article, we consider extensions of the multistage carcinogenesis model by mixture modeling. This approach allows us to describe population heterogene...
Autores principales: | Gsteiger, Sandro, Morgenthaler, Stephan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515834/ https://www.ncbi.nlm.nih.gov/pubmed/18644142 http://dx.doi.org/10.1186/1742-4682-5-13 |
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