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Depression in Parkinson’s disease: Health risks, etiology, and treatment options
Depression is found in about 30%–40% of all patients with Parkinson’s disease (PD), but only a small percentage (about 20%) receive treatment. As a consequence, many PD patients suffer with reduced health-related quality of life. To address quality of life in depressed PD patients, we reviewed the l...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515908/ https://www.ncbi.nlm.nih.gov/pubmed/18728814 |
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author | Frisina, Pasquale G Borod, Joan C Foldi, Nancy S Tenenbaum, Harriet R |
author_facet | Frisina, Pasquale G Borod, Joan C Foldi, Nancy S Tenenbaum, Harriet R |
author_sort | Frisina, Pasquale G |
collection | PubMed |
description | Depression is found in about 30%–40% of all patients with Parkinson’s disease (PD), but only a small percentage (about 20%) receive treatment. As a consequence, many PD patients suffer with reduced health-related quality of life. To address quality of life in depressed PD patients, we reviewed the literature on the health correlates of depression in PD (eg, cognitive function), etiology of depression in PD, and treatment options (ie, antidepressants, electroconvulsive therapy, and psychotherapy). The current review is unique in its focus on psychosocial aspects, as well as neuropathological factors, of depression in PD. Overall, we conclude that neurochemical (eg, serotonin) and psychosocial factors (eg, coping style, self-esteem, and social support) contribute to the affective disturbances found in this neuropsychiatric population. Therefore, we recommend that a multidisciplinary (eg, pharmacotherapeutic, psychoeducational, and/or psychotherapeutic) approach to treatment be taken with depressed PD patients. |
format | Text |
id | pubmed-2515908 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-25159082008-08-26 Depression in Parkinson’s disease: Health risks, etiology, and treatment options Frisina, Pasquale G Borod, Joan C Foldi, Nancy S Tenenbaum, Harriet R Neuropsychiatr Dis Treat Review Depression is found in about 30%–40% of all patients with Parkinson’s disease (PD), but only a small percentage (about 20%) receive treatment. As a consequence, many PD patients suffer with reduced health-related quality of life. To address quality of life in depressed PD patients, we reviewed the literature on the health correlates of depression in PD (eg, cognitive function), etiology of depression in PD, and treatment options (ie, antidepressants, electroconvulsive therapy, and psychotherapy). The current review is unique in its focus on psychosocial aspects, as well as neuropathological factors, of depression in PD. Overall, we conclude that neurochemical (eg, serotonin) and psychosocial factors (eg, coping style, self-esteem, and social support) contribute to the affective disturbances found in this neuropsychiatric population. Therefore, we recommend that a multidisciplinary (eg, pharmacotherapeutic, psychoeducational, and/or psychotherapeutic) approach to treatment be taken with depressed PD patients. Dove Medical Press 2008-02 2008-02 /pmc/articles/PMC2515908/ /pubmed/18728814 Text en © 2008 Dove Medical Press Limited. All rights reserved |
spellingShingle | Review Frisina, Pasquale G Borod, Joan C Foldi, Nancy S Tenenbaum, Harriet R Depression in Parkinson’s disease: Health risks, etiology, and treatment options |
title | Depression in Parkinson’s disease: Health risks, etiology, and treatment options |
title_full | Depression in Parkinson’s disease: Health risks, etiology, and treatment options |
title_fullStr | Depression in Parkinson’s disease: Health risks, etiology, and treatment options |
title_full_unstemmed | Depression in Parkinson’s disease: Health risks, etiology, and treatment options |
title_short | Depression in Parkinson’s disease: Health risks, etiology, and treatment options |
title_sort | depression in parkinson’s disease: health risks, etiology, and treatment options |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515908/ https://www.ncbi.nlm.nih.gov/pubmed/18728814 |
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