Resolving Individuals Contributing Trace Amounts of DNA to Highly Complex Mixtures Using High-Density SNP Genotyping Microarrays

We use high-density single nucleotide polymorphism (SNP) genotyping microarrays to demonstrate the ability to accurately and robustly determine whether individuals are in a complex genomic DNA mixture. We first develop a theoretical framework for detecting an individual's presence within a mixt...

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Detalles Bibliográficos
Autores principales: Homer, Nils, Szelinger, Szabolcs, Redman, Margot, Duggan, David, Tembe, Waibhav, Muehling, Jill, Pearson, John V., Stephan, Dietrich A., Nelson, Stanley F., Craig, David W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516199/
https://www.ncbi.nlm.nih.gov/pubmed/18769715
http://dx.doi.org/10.1371/journal.pgen.1000167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516199/
https://www.ncbi.nlm.nih.gov/pubmed/18769715
http://dx.doi.org/10.1371/journal.pgen.1000167

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