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The incoherent feed-forward loop can generate non-monotonic input functions for genes
Gene regulation networks contain recurring circuit patterns called network motifs. One of the most common network motif is the incoherent type 1 feed-forward loop (I1-FFL), in which an activator controls both gene and repressor of that gene. This motif was shown to act as a pulse generator and respo...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516365/ https://www.ncbi.nlm.nih.gov/pubmed/18628744 http://dx.doi.org/10.1038/msb.2008.43 |