Superior Immunogenicity of Inactivated Whole Virus H5N1 Influenza Vaccine is Primarily Controlled by Toll-like Receptor Signalling

In the case of an influenza pandemic, the current global influenza vaccine production capacity will be unable to meet the demand for billions of vaccine doses. The ongoing threat of an H5N1 pandemic therefore urges the development of highly immunogenic, dose-sparing vaccine formulations. In unprimed...

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Detalles Bibliográficos
Autores principales: Geeraedts, Felix, Goutagny, Nadege, Hornung, Veit, Severa, Martina, de Haan, Aalzen, Pool, Judith, Wilschut, Jan, Fitzgerald, Katherine A., Huckriede, Anke
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516931/
https://www.ncbi.nlm.nih.gov/pubmed/18769719
http://dx.doi.org/10.1371/journal.ppat.1000138

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