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Closed Chromatin Architecture Is Induced by an RNA Duplex Targeting the HIV-1 Promoter Region

In some mammalian systems small interfering RNAs (siRNA) targeting homologous sequences in promoter regions of genes induce transcriptional gene silencing (TGS). We have previously reported the induction of TGS by an siRNA (prom-A siRNA) targeting the tandem NF-κB-binding motifs within the human imm...

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Detalles Bibliográficos
Autores principales:	Suzuki, Kazuo, Juelich, Torsten, Lim, Heidi, Ishida, Takaomi, Watanebe, Toshiki, Cooper, David A., Rao, Sudha, Kelleher, Anthony D.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Transcription, Chromatin, and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516975/ https://www.ncbi.nlm.nih.gov/pubmed/18519571 http://dx.doi.org/10.1074/jbc.M709651200

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