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RNA interference-mediated gene silencing in murine T cells: in vitro and in vivo validation of proinflammatory target genes

BACKGROUND: T cells play a central role in many inflammatory diseases, hence the identification and validation of T cell-specific target genes will increase the understanding of T cell function in pathologic inflammatory situations. RNA interference (RNAi), with its ability to induce specific gene s...

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Detalles Bibliográficos
Autores principales: Gust, Tatjana C, Neubrandt, Luisa, Merz, Claudia, Asadullah, Khusru, Zügel, Ulrich, von Bonin, Arne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517589/
https://www.ncbi.nlm.nih.gov/pubmed/18684324
http://dx.doi.org/10.1186/1478-811X-6-3