Heavily glycosylated, highly fit SIVMne variants continue to diversify and undergo selection after transmission to a new host and they elicit early antibody dependent cellular responses but delayed neutralizing antibody responses

BACKGROUND: Lentiviruses such as human and simian immunodeficiency viruses (HIV and SIV) undergo continual evolution in the host. Previous studies showed that the late-stage variants of SIV that evolve in one host replicate to significantly higher levels when transmitted to a new host. However, it i...

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Detalles Bibliográficos
Autores principales: Eastman, Dawnnica, Piantadosi, Anne, Wu, Xueling, Forthal, Donald N, Landucci, Gary, Kimata, Jason T, Overbaugh, Julie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518139/
https://www.ncbi.nlm.nih.gov/pubmed/18680596
http://dx.doi.org/10.1186/1743-422X-5-90

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