Cargando…

Differentiating Protein-Coding and Noncoding RNA: Challenges and Ambiguities

The assumption that RNA can be readily classified into either protein-coding or non-protein–coding categories has pervaded biology for close to 50 years. Until recently, discrimination between these two categories was relatively straightforward: most transcripts were clearly identifiable as protein-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dinger, Marcel E., Pang, Ken C., Mercer, Tim R., Mattick, John S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518207/ https://www.ncbi.nlm.nih.gov/pubmed/19043537 http://dx.doi.org/10.1371/journal.pcbi.1000176

Ejemplares similares

NRED: a database of long noncoding RNA expression
por: Dinger, Marcel E., et al.
Publicado: (2009)

Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation
por: Mercer, Tim R, et al.
Publicado: (2010)

RNAdb 2.0—an expanded database of mammalian non-coding RNAs
por: Pang, Ken C., et al.
Publicado: (2007)

Genome-wide analysis of long noncoding RNA stability
por: Clark, Michael B., et al.
Publicado: (2012)

lncRNAdb: a reference database for long noncoding RNAs
por: Amaral, Paulo P., et al.
Publicado: (2011)

Long noncoding RNAs and the genetics of cancer
por: Cheetham, S W, et al.
Publicado: (2013)

The extent of functionality in the human genome
por: Mattick, John S, et al.
Publicado: (2013)

Probing the phenomics of noncoding RNA
por: Mattick, John S
Publicado: (2013)

The Genetic Signatures of Noncoding RNAs
por: Mattick, John S.
Publicado: (2009)

Realizing the significance of noncoding functionality in clinical genomics
por: Gloss, Brian S., et al.
Publicado: (2018)

Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage
por: Bracken, Cameron P., et al.
Publicado: (2011)

RNAdb—a comprehensive mammalian noncoding RNA database
por: Pang, Ken C., et al.
Publicado: (2005)

Improved definition of the mouse transcriptome via targeted RNA sequencing
por: Bussotti, Giovanni, et al.
Publicado: (2016)

Long noncoding RNAs in cancer: mechanisms of action and technological advancements
por: Bartonicek, Nenad, et al.
Publicado: (2016)

Tolerance of ambiguity and psychological well‐being in medical training: A systematic review
por: Hancock, Jason, et al.
Publicado: (2019)

The Functional Characterization of Long Noncoding RNA SPRY4-IT1 in Human Melanoma Cells
por: Mazar, Joseph, et al.
Publicado: (2014)

Long noncoding RNA: noncoding and not coded
por: Toiber, Debra, et al.
Publicado: (2017)

Long noncoding RNA: noncoding and not coded
por: Toiber, Debra, et al.
Publicado: (2017)

The State of Long Non-Coding RNA Biology
por: Mattick, John S.
Publicado: (2018)

Saccharopolyspora erythraea’s genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch
por: Marcellin, Esteban, et al.
Publicado: (2013)

Pregnancy-Induced Noncoding RNA (PINC) Associates with Polycomb Repressive Complex 2 and Regulates Mammary Epithelial Differentiation
por: Shore, Amy N., et al.
Publicado: (2012)

High resolution temporal transcriptomics of mouse embryoid body development reveals complex expression dynamics of coding and noncoding loci
por: Gloss, Brian S., et al.
Publicado: (2017)

Challenges in describing the conformation and dynamics of proteins with ambiguous behavior
por: Roca-Martinez, Joel, et al.
Publicado: (2022)

Regulated Expression of PTPRJ/CD148 and an Antisense Long Noncoding RNA in Macrophages by Proinflammatory Stimuli
por: Dave, Richa K., et al.
Publicado: (2013)

ANGIOGENES: knowledge database for protein-coding and noncoding RNA genes in endothelial cells
por: Müller, Raphael, et al.
Publicado: (2016)

Exploring the Role of Non-Coding RNAs in the Pathophysiology of Systemic Lupus Erythematosus
por: Taheri, Mohammad, et al.
Publicado: (2020)

Perspectives on the Role of Non-Coding RNAs in the Regulation of Expression and Function of the Estrogen Receptor
por: Taheri, Mohammad, et al.
Publicado: (2020)

Pre-mRNA splicing: from protein-coding to noncoding RNAs
por: Bindereif, Albrecht
Publicado: (2015)

Understanding the regulatory and transcriptional complexity of the genome through structure
por: Mercer, Tim R., et al.
Publicado: (2013)

Differential protein‐coding gene and long noncoding RNA expression in smoking‐related lung squamous cell carcinoma
por: Li, Shicheng, et al.
Publicado: (2017)

Incredible RNA: Dual Functions of Coding and Noncoding
por: Nam, Jin-Wu, et al.
Publicado: (2016)

Genome-wide discovery of human splicing branchpoints
por: Mercer, Tim R., et al.
Publicado: (2015)

Noncoding-RNA-Based Therapeutics with an Emphasis on Prostatic Carcinoma—Progress and Challenges
por: Nava, Victor E., et al.
Publicado: (2022)

Identification of a dinucleotide signature that discriminates coding from non-coding long RNAs
por: Ulveling, Damien, et al.
Publicado: (2014)

Introme accurately predicts the impact of coding and noncoding variants on gene splicing, with clinical applications
por: Sullivan, Patricia J., et al.
Publicado: (2023)

Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression
por: Zeraati, Mahdi, et al.
Publicado: (2017)

Clusters of Internally Primed Transcripts Reveal Novel Long Noncoding RNAs
por: Furuno, Masaaki, et al.
Publicado: (2006)

Navigating the dynamic landscape of long noncoding RNA and protein-coding gene annotations in GENCODE
por: Jalali, Saakshi, et al.
Publicado: (2016)

Targeted, High-Resolution RNA Sequencing of Non-coding Genomic Regions Associated With Neuropsychiatric Functions
por: Hardwick, Simon A., et al.
Publicado: (2019)

Coding of level of ambiguity within neural systems mediating choice
por: Lopez-Paniagua, Dan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_urk19lvjt4f0l5t5k1ko9s918m